Philip S. Pharazyn
OBJECTIVE:
To obtain a position designing, discovering and developing synthetic methods using my experience in multi-step synthesis, purification and characterization.
EDUCATION:
Ph.D., Organic Chemistry, Washington State University, Pullman, WA, 2004
Thesis Title: Asymmetric Syntheses of Boronic Esters with Applications Towards Kainoids and Cesium Trifluoroborates
Thesis Advisor: Donald S. Matteson
B.S., Chemistry, Nebraska Wesleyan University, Lincoln, NE, 1994
RELEVANT EXPERIENCE:
Postdoctoral Fellow
Colorado State University
Department of Chemistry
8/2/2010 – 4/30/2012
• Electron paramagnetic resonance spectroscopy investigations of the magnesium environment in the base excision repair enzyme DNA polymerase beta.
• Microwave-assisted synthesis of vanadyl porphyrins
• Mentoring of undergraduate students in the synthesis of targeted biologically active organometallic complexes.
• Outreach to local grade schools.
• Substitute lecturer for undergraduate organic chemistry courses.
2006-2010
• Worked at a trucking company while searching for a position in the chemical industry and staying current with research topics.
Production Chemist
TCI America
1/3/2006 – 6/30/2006
• Member of the Chemical Hygiene Plan committee.
• Synthesis from gram to multi-kilogram scale.
• Multi-step custom syntheses for customer orders.
• cGMP trained.
• Cost estimates for custom synthesis requests.
• Hazardous waste destruction.
• Repacks of chemicals to fit customer needs.
Postdoctoral Fellow
Washington State University
Department of Chemistry
1/1/2005 – December 31, 2005
• Worked on developing a new class of hydroboration reagents that would have had more selectivity and higher yields than 9-BBN.
• Worked on developing a new route to kainic acid and its derivatives using carbon-carbon coupling as a key step.
Graduate Research & Teaching Assistant
Washington State University
Department of Chemistry
8/16/1996 – 12/31/2004
• Produced multi-step asymmetric synthesis analogs of the neuroexcitant and Alzheimer’s disease research compound kainic acid using boronic ester chemistry.
• Performed multi-step asymmetric synthesis of the drugstore beetle, Stegobium paniceum, and furniture beetle, Anobium punctatum, pheromone stegobinone using boronic ester chemistry for use in insect traps in the United States to prevent crop destruction.
• Completed multi-step asymmetric syntheses of the four insect pheromone isomers of 4-methyl-3-heptanol ((3S,4S)-4-methyl-3-heptanol (aggregation pheromone of the European elm bark beetle Scolytus multistriatus), (3S,4R)-4-methyl-3-heptanol (SE Asian ant trail pheromone), (3R,4S)-4-methyl-3-heptanol, and (3R,4R)-4-methyl-3-heptanol) using boronic ester chemistry for use in insect traps in Sweden.
• Worked on the production of a new boronic ester reagent that would allow for the synthesis of asymmetric primary, secondary and tertiary aldehydes that could be used in Suzuki couplings and Liebeskind-Srogl couplings.
• Taught organic chemistry laboratories (included giving pre-lab lectures, safety instruction, writing and grading quizzes, grading of laboratory reports, modifying preparation of the local anesthetic, lidocaine, for use as a laboratory final exam, and scheduling of laboratory experiments).
AALAS Animal Care and Use Certification
2/19/1997
Undergraduate Research
Nebraska Wesleyan University
1992-1994
• Redesigned organic teaching laboratory experiments to reduce waste production of toxic chemicals (i.e. halogenated solvents).
• ...
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